TY - JOUR AU - Mahal,Ajay AU - O'Flaherty,Brendan AU - Bloom,David E. TI - Needle Sharing and HIV Transmission: A Model with Markets and Purposive Behavior JF - National Bureau of Economic Research Working Paper Series VL - No. 14823 PY - 2009 Y2 - March 2009 UR - http://www.nber.org/papers/w14823 L1 - http://www.nber.org/papers/w14823.pdf N1 - Author contact info: Ajay Mahal Harvard School of Public Health Department of Global Health and Population 665 Huntington Ave Boston, MA 02115 E-Mail: amahal@hsph.harvard.edu Brendan O'Flaherty Columbia University E-Mail: bo2@columbia.edu David E. Bloom Harvard School of Public Health Department of Global Health and Population 665 Huntington Ave. Boston, MA 02115 Tel: 617/432-0866 Fax: 617/432-6733 E-Mail: dbloom@hsph.harvard.edu AB - Without well designed empirical studies, mathematical models are an important way to use data on needle infection for inferences about human infection. We develop a model with explicit behavioral foundations to explore an array of policy interventions related to HIV transmission among IDU. In our model, needle exchanges affect the spread of HIV in three ways: more HIV-negative IDUs use new needles instead of old ones; needles are retired after fewer uses; and the proportion of HIV-positive IDUs among users of both old and new needles rises owing to sorting effects. The first and second effects reduce the long-run incidence of HIV, while the third effect works in the opposite direction. We compare the results of our model with those of Kaplan and O'Keefe (1993) that is the foundation of many later models of HIV transmission among IDU. ER -