TY - JOUR AU - Azoulay,Pierre AU - Zivin,Joshua S. Graff AU - Manso,Gustavo TI - Incentives and Creativity: Evidence from the Academic Life Sciences JF - National Bureau of Economic Research Working Paper Series VL - No. 15466 PY - 2009 Y2 - October 2009 UR - http://www.nber.org/papers/w15466 L1 - http://www.nber.org/papers/w15466.pdf N1 - Author contact info: Pierre Azoulay MIT Sloan School of Management 100 Main Street, E62-482 Cambridge, MA 02142 Tel: 617/258-9766 Fax: 617/253-2660 E-Mail: pazoulay@mit.edu Joshua S. Graff Zivin University of California, San Diego 9500 Gilman Drive, MC 0519 La Jolla, CA 92093-0519 Tel: 858/822-6438 E-Mail: jgraffzivin@ucsd.edu Gustavo Manso MIT Sloan School E-Mail: manso@mit.edu AB - Despite its presumed role as an engine of economic growth, we know surprisingly little about the drivers of scientific creativity. In this paper, we exploit key differences across funding streams within the academic life sciences to estimate the impact of incentives on the rate and direction of scientific exploration. Specifically, we study the careers of investigators of the Howard Hughes Medical Institute (HHMI), which tolerates early failure, rewards long-term success, and gives its appointees great freedom to experiment; and grantees from the National Institute of Health, which are subject to short review cycles, pre-defined deliverables, and renewal policies unforgiving of failure. Using a combination of propensity-score weighting and difference-in-differences estimation strategies, we find that HHMI investigators produce high- impact papers at a much higher rate than a control group of similarly-accomplished NIH-funded scientists. Moreover, the direction of their research changes in ways that suggest the program induces them to explore novel lines of inquiry. ER -